Premiere 6.5 has been announced last week and is carbonized for OS X. Give it a month or two to ship if it isn't already and you will have that option.
MOTU has released a flurry of drivers for their audio and MIDI hardware that seem to work well with a few freeware MIDI apps. Digital Performer has been announced for "4th quarter 2002". Emagic will probably be sooner than that with Logic. Audio apps are appearing right and left such as Peak and Spark. No mention of ProTools though...
Things are coming together and not long after the 10.2 release I suspect that releases will accelerate.
Other than cost, the software is appearing exponentially.